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1. An antagonist binds to a receptor and blocks it and therefore, produces no effect?
2. Salbutamol is a β2 adrenoceptor antagonist and leads to smooth muscle constriction in the lungs?
3. Propranolol is a β2 adrenoceptor agonist and leads to smooth muscle relaxation in lungs?
4. In Parkinson’s Disease there is a relative deficiency of dopamine and an excess of acetylcholine?
5. Parkinson’s Disease can be treated using a dopamine antagonist?
6. Parkinson’s Disease can be treated using an acetylcholine agonist?
7. Parkinson’s Disease can be treated by blocking enzymes that break down dopamine?
8. Non-steroidal anti inflammatory drugs (NSAIDS) work by blocking cyclo-oxygenase leading to a reduction in inflammation and pain?
9. Ions are transported via specialist enzymes called pumps?
10. Drugs called proton pump inhibitors, such as omeprazole and lansoprazole, block the proton pump and reduce the acidity of the stomach?
Question 1: The correct answer is True An antagonist binds to a receptor and blocks it and therefore, produces no effect.
Question 2: The correct answer is False Salbutamol is a β2 adrenoceptor antagonist and leads to smooth muscle constriction in the lungs - Salbutamol is a β2 adrenoceptor agonist which leads to smooth muscle bronchodilations in lungs.
Question 3: The correct answer is False Propranolol is a β2 adrenoceptor agonist and leads to smooth muscle relaxation in lungs - Propranolol is a β2 adrenoceptor antagonist which leads to smooth muscle bronchoconstriction.
Question 4: The correct answer is True In Parkinson’s Disease there is a relative deficiency of dopamine and an excess of acetylcholine.
Question 5: The correct answer is False Parkinson’s Disease can be treated using a dopamine antagonist - Dopamine agonists are used to treat Parkinson’s Disease symptoms.
Question 6: The correct answer is False Parkinson’s Disease can be treated using an acetylcholine agonist - Acetylcholine agonists or anticholinergics are used to treat Parkinson’s disease.
Question 7: The correct answer is True Parkinson’s Disease can be treated by blocking enzymes that break down dopamine - Dopamine in the form of levodopa is given with decarboxylase inhibitors to prevent its breakdown outside the brain. Levodopa readily crosses the blood-brain barrier.
Question 8: The correct answer is True Non-steroidal anti inflammatory drugs (NSAIDS) work by blocking cyclo-oxygenase leading to a reduction in inflammation and pain.
Question 9: The correct answer is True Ions are transported via specialist enzymes called pumps - Ions are transported via an ion transporter (or ion pump) which is an enzyme-linked transmembrane protein.
Question 10: The correct answer is True Drugs called proton pump inhibitors, such as omeprazole and lansoprazole, block the proton pump and reduce the acidity of the stomach.
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