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Question 1: The correct answer is True Drugs may exert an effect by affecting neurotransmission, by inhibiting the action of enzymes, or by affecting the secretion or transport of biochemicals or ions. - All of these are ways drugs can exert their effects.

Question 2: The correct answer is True Neurotransmitters are released into the synaptic cleft from nerve endings following an electrical impulse.

Question 3: The correct answer is True Neurotransmitters cross the synaptic cleft and bind to post-synaptic nerve endings to exert their effect.

Question 4: The correct answer is True The effect of neurotransmitters can be terminated through reuptake into the pre-synaptic nerve ending.

Question 5: The correct answer is True The effect of neurotransmitters can be terminated through inactivation by enzymes.

Question 6: The correct answer is True A neurotransmitter may have different actions in different parts of the body depending on the location of sub-types of receptors.

Question 7: The correct answer is True Adrenoceptors are subclassified into α1, α2, β1, β2 and β3 receptors.

Question 8: The correct answer is False Acetylcholine is the endogenous ligand for adrenoceptors. - Acetylcholine is the endogenous ligand for cholinergic receptors.

Question 9: The correct answer is False Selective serotonin re-uptake inhibitors (SSRIs) such as fluoxetine decrease the amount of serotonin available in the synapse and therefore, decrease its effect. - SSRIs prevent re-uptake of serotonin back in to the synapse making more available to exert its action on receptors.

Question 10: The correct answer is TrueAn agonist binds to a receptor and activates it producing an effect.

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