A 67 year old man has been prescribed dihydrocodeine 30mg every 4 hours for mild to moderate joint pain. Which TWO of the following potential adverse drug reactions are most likely to be caused by the drug

- Sweating

- Rash

- Constipation

- Hypotension

- Nausea and vomiting

Common ADRs
From the BNF, the most common adverse drug reactions from this list are nausea and vomiting, and constipation. Dihydrocodeine and other opioid analgesics should be used with caution long term in non-malignant disease.

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